Hippocampal atrophy in epilepsy

Clarissa Lin Yasuda MD PhD (Dr. Yasuda of the University of Campinas - UNICAMP has no relevant financial relationships to disclose.)
Fernando Cendes MD PhD (Dr. Cendes of the University of Campinas - UNICAMP has no relevant financial relationships to disclose.)
Jerome Engel Jr MD PhD, editor. (Dr. Engel of the David Geffen School of Medicine at the University of California, Los Angeles, has no relevant financial relationships to disclose.)
Originally released December 30, 2014; last updated January 30, 2017; expires January 30, 2020

Overview

In this article, the authors present data and discussion about the causes, syndromes, diagnosis, and management of hippocampal atrophy and epilepsy.

Key points

 

• Hippocampal atrophy associated with mesial temporal lobe epilepsy is 1 of the most frequent forms of epilepsy with focal onset.

 

• Some patients have good response to antiepileptic drug (AED) treatment, whereas most patients are pharmacoresistant.

 

• Surgical treatment yields better seizure control when compared to medical treatment in those who failed initial AED treatment.

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