Multiple sclerosis: management

Anthony T Reder MD (Dr. Reder of the University of Chicago served on advisory boards and as a consultant for Bayer, Biogen Idec, Caremark Rx, Genentech, Genzyme, Novartis, Malinkrodt, Serono, and Teva-Marion.)
Originally released October 23, 2014; last updated July 3, 2018; expires July 3, 2021

Overview

Multiple sclerosis affects every part of the neuraxis and has replaced syphilis as the great mimicker in neurology. In this article, author discusses treatment of multiple sclerosis symptoms and the underlying disease as well as successes and failures in therapeutic trials and critical issues regarding multiple sclerosis therapy. This revision includes new comments on environment and vitamin D and the immunology, benefits, and dangers of treatments.

Key points

 

• Multiple sclerosis symptoms arise from lesion in all parts of the CNS; most symptoms can be treated.

 

• New therapies have dramatically changed the course of multiple sclerosis and survival. There are fewer exacerbations and hospitalizations and less progression of the disease compared to the 1993 pre-therapy era.

 

• The best therapy and best compliance to therapy is based on a decision by doctor and patient that incorporate disease characteristics, dangers from other medical conditions, patient s preference for form of administration, and life style. Delay and switch of therapy by insurance companies and other decision makers who are not familiar with the patient or with the disease often lead to permanent brain damage.

 

• On average, all therapies are still only partially effective.

 

• There is intense research to find the cause and cure of multiple sclerosis.

The content you are trying to view is available only to logged in, current MedLink Neurology subscribers.

If you are a subscriber, please log in.

If you are a former subscriber or have registered before, please log in first and then click select a Service Plan or contact Subscriber Services. Site license users, click the Site License Acces link on the Homepage at an authorized computer.

If you have never registered before, click Learn More about MedLink Neurology  or view available Service Plans.