Historical note and terminology
Pemoline is a central nervous system stimulant, but it is structurally dissimilar to amphetamines and methylphenidate. Pemoline was approved by the United States Food and Drug Administration in 1975. In 1999, pemoline was withdrawn in Canada due to liver complications. In 2005, the manufacturer withdrew pemoline in the United States after a consumer group petitioned the FDA about its safety.
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