Aug 03, 2017
Most newborns with epilepsy benefit from genetic testing
Research published in Neurology analyzed data from the Neonatal Seizure Registry that includes enrollees from 7 children's hospitals. It found that most newborns with epilepsy would benefit from genetic testing because the majority of cases are linked to identifiable genetic causes.
Feb 09, 2017
Gene variant identified for Kawasaki disease susceptibility
Researchers have conducted novel whole genome sequencing of a family in which 2 of 4 children were affected by Kawasaki disease, and have identified plausible gene variants that predispose some children to developing the disease. The findings are published in the PLOS ONE.
Dec 13, 2016
Research identifies a molecular basis for common congenital brain defect
Scientists have discovered a molecular cause of hydrocephalus. Because the same molecule is also implicated in Down syndrome, the finding, published today in the Journal of Neuroscience, may explain the 10-fold increased risk of hydrocephalus in infants born with Down syndrome.
Aug 16, 2016
Most physicians recognize shaken baby syndrome as a medical diagnosis
A University of Colorado School of Medicine researcher and colleagues have conducted the first-ever survey of physicians on the validity of "abusive head trauma" as a medical diagnosis, due to recent controversy on the subject. The survey results provide empiric data that clearly support the conclusion that shaken baby syndrome and abusive head trauma are generally accepted as valid medical diagnoses by a broad range of medical specialists.
Aug 05, 2016
Microcephaly discoveries made in non-Zika cases help explain abnormal brain growth
In 2 new papers in the American Journal of Human Genetics, researchers report new findings about a key protein - CIT - involved in the process that generates the many new cells required to build a normal size brain. Though the new studies didn't involve Zika-related microcephaly, they may provide clues that other scientists can use to investigate how Zika virus disrupts brain development, and my also provide insight into what is required for brains to develop normally.
Jan 04, 2016
Chronic traumatic encephalopathy in 25-year-old former football player
In an article published online by JAMA Neurology, Boston University School of Medicine authors write an observation letter about chronic traumatic encephalopathy (CTE) pathology in a 25-year-old former college football player who experienced more than 10 concussions while playing football, the first occurring when he was 8 years old. The authors note that, to their knowledge, this is the first autopsy-confirmed case to include neuropsychological testing to document the type of cognitive issues that present with CTE.
Oct 08, 2015
Protecting newborn brains using hypothermia
A unique study at Children’s Hospital Los Angeles of newborns treated with hypothermia for hypoxic-ischemic encephalopathy confirms its neuroprotective effects on the brain. The findings, showing that neuroprotection is achieved by realizing a specific balance between energy metabolism and neurotransmission, were published October 7 by the Journal of Cerebral Blood Flow and Metabolism.
Oct 01, 2015
Colds, flu may temporarily increase stroke risk in kids
Stroke is very rare in children, but colds, flu, and other minor infections may temporarily increase stroke risk in children, according to a study published in the September 30, 2015, online issue of Neurology®. The study also found routine childhood vaccines may decrease the risk of stroke.