Cerebral arteriopathies

Aneesh B Singhal MD (

Dr. Singhal of Harvard Medical School received consulting fees from Deck Therapeutics and Omniox, and his wife is an employee and owns stock in Biogen.

Eva A Rocha MD (

Dr. Rocha of Universidade Federal de São Paulo has no relevant financial relationships to disclose.

Steven R Levine MD, editor. (

Dr. Levine of the SUNY Health Science Center at Brooklyn has no relevant financial relationships to disclose.

Originally released December 18, 2001; last updated April 4, 2020; expires April 4, 2023


In this article, the authors present an approach to the diagnosis and management of cerebral arteriopathies. Several important entities are briefly reviewed, including carotid and vertebral arterial dissection, moyamoya disease, reversible cerebral vasoconstriction syndromes, primary angiitis of the central nervous system, dolichoectasia, sickle cell disease, CADASIL, Fabry disease, and selected genetic and inherited arteriopathies.

Key points


• Cerebral arteriopathies are a diverse group of disorders requiring a high index of suspicion and reliance on clinical and imaging clues for diagnosis.


• Small-vessel arteriopathies may not be revealed on cerebral angiography.


• Accurate diagnosis is important because individual cerebral arteriopathies have unique management and prognostic implications.

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