Stroke therapy

Carolyn D Brockington MD (

Dr. Brockington, Director of the Stroke Center at Mount Sinai Morningside and Mount Sinai West, has no relevant financial relationships to disclose

Steven R Levine MD, editor. (

Dr. Levine of the SUNY Health Science Center at Brooklyn has no relevant financial relationships to disclose.

Originally released August 14, 2001; last updated January 7, 2021; expires January 7. 2024


The treatment of acute ischemic stroke is considered an emergency. The clock starts with the interruption of blood flow to the brain. The goal of each therapeutic intervention is to reestablish blood flow to viable brain tissue to reduce the degree of injury. Since the FDA approval of intravenous tPA for acute ischemic stroke in 1996, the options for treatment have increased considerably. Despite the advances, the key to good clinical outcomes remains the same with rapid identification of patients coupled with fast assessment and treatment. This update contains the latest information on the treatment and management of acute ischemic stroke.

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