The researchers have determined that gum disease (gingivitis) plays a decisive role in whether a person developes Alzheimer disease or not.
"We discovered DNA-based proof that the bacteria causing gingivitis can move from the mouth to the brain," says researcher Piotr Mydel at Broegelmanns Research Laboratory, Department of Clinical Science, University of Bergen (UiB).
The bacteria produces a protein that destroys nerve cells in the brain, which in turn leads to loss of memory and ultimately, Alzheimer disease.
Brush your teeth for better memory
Mydel points out that the bacteria is not causing Alzheimer disease alone, but the presence of these bacteria raise the risk for developing the disease substantially and are also implicated in a more rapid progression of the disease. However, the good news is that this study shows that there are some things you can do yourself to slow down Alzheimer disease.
"Brush your teeth and use floss." Mydel adds that it is important, if you have established gingivitis and have Alzheimer disease in your family, to go to your dentist regularly and clean your teeth properly.
New medicine being developed
Researchers have previously discovered that the bacteria causing gingivitis can move from the mouth to the brain where theharmful enzymes they excrete can destroy the nerve cells in the brain. Now, for the first time, Mydel has DNA-evidence for this process from human brains. Mydel and his colleagues examined 53 persons with Alzheimer disease and discovered the enzyme in 96% of the cases. According to Mydel, this knowledge gives researchers a possible new approach for attacking Alzheimer disease.
"We have managed to develop a drug that blocks the harmful enzymes from the bacteria, postponing the development of Alzheimer disease. We are planning to test this drug later this year," says Piotr Mydel.
Source: News Release
University Of Bergen
June 3, 2019