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Brainstem glioma (13)

Enhanced T1-weighted MRI (TR 750/TE 32) scans of patient shown in Brainstem glioma (7), (9), and (12), demonstrating a partial response (50% to 90% reduction of tumor volume) of the pontine anaplastic astrocytoma to chemotherapy with intraarterial carboplatin and intravenous etoposide. (A and C) Prechemotherapy baseline scans of enhancing brainstem lesion. (B and D) Same images as A and C, following 2 cycles of chemotherapy, showing significant reduction in tumor volume and enhancement. (Contributed by Dr. Herbert Newton.)