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The oligodendrocyte nucleus and cytoplasm are well preserved. Cell organelles, including 15 to 20 mitochondria, are visible. (Contributed by Dr. Raphael Schiffmann.)
Stroke & Vascular Disorders
Mar. 18, 2021
Generalized neuromyotonia is usually an autoimmune disease characterized by widespread muscle stiffness and delayed muscle relaxation after voluntary movement. It is accompanied by continuous muscle twitching known as myokymia. Both conditions are typically related to disorders of the voltage-gated potassium channel and caused by autoimmune, toxic, or genetic processes. Whereas neuromyotonia is specific to these disorders, myokymia can be seen in many neurologic conditions.
May. 03, 2021
Diabetic neuropathies include a variety of disorders that afflict diabetics fairly exclusively and are characterized by variable degrees of peripheral nerve damage. Although chronic distal sensorimotor polyneuropathy is the most common type of diabetic neuropathy, other generalized and focal acute and chronic diabetic neuropathies are not uncommonly encountered in neurologic clinical practice.
Jan. 02, 2021
The authors discuss the clinical manifestations of acrylamide neuropathy. This toxic neuropathy has served as a model for studying the effects of toxins
Jun. 22, 2021
Childhood Degenerative & Metabolic Disorders
Sep. 05, 2020
Pneumococcal meningitis symptoms typically include fever, headache, nausea, vomiting, irritability, and lethargy proceeding to further clouding of consciousness. The course can involve rapid neurologic deterioration leading to respiratory arrest and death. Patients with a basilar skull or cribriform fracture with a CSF leak are at increased risk of acquiring pneumococcal meningitis.
Jul. 20, 2021
Jun. 01, 2020
Peripheral neuropathy refers to any condition that injures peripheral nerves, whether acquired or hereditary, systemic or restricted to peripheral nerves, or mildly symptomatic or disabling and severe. Anatomic classification of neuropathy includes (1) fiber type (motor vs. sensory, large vs. small, somatic vs. autonomic), (2) portion of fiber affected (axon vs. myelin), and (3) distribution of nerves affected (length-dependent, length-independent, focal, and multifocal).
Jun. 17, 2021