Behavioral & Cognitive Disorders
Familial Alzheimer disease
Familial Alzheimer disease refers to cases where a clear pattern of inheritance within a family is established. Memory loss, particularly declarative memory, is the most important symptom, and is under the strongest genetic influence. Clinical manifestations do not seem to be different from those with the sporadic form of this illness, but early-onset dementia, early myoclonus, and a familial history of dementia should suggest the possibility of a genetic form of Alzheimer disease.
Oct. 28, 2013