Neurotoxicology
Pyridoxine deficiency and toxicity
May. 01, 2024
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Toll Free (U.S. + Canada): 800-452-2400
US Number: +1-619-640-4660
Support: service@medlink.com
Editor: editor@medlink.com
ISSN: 2831-9125
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This photograph, from a 45-year-old woman from the Ivory Coast, depicts what is known as a tibial sabre deformity, which resulted from a late tertiary yaws infection. This patient’s Venereal Disease Research Laboratory test, or VDRL, produced a positive result of 1:16 and was accompanied by the microhemagglutination assay (MHA-TP) test, which was also reactive, or positive. A saber shin deformity is an abnormality of the tibia characterized by marked anterior bowing of the lower leg. This defect may be seen in some children with congenital syphilis and patients with yaws. (Source: Photography by Dr. Peter Perine, Centers for Disease Control and Prevention, 1979. Public Health Image Library ID# 3823, Centers for Disease Control and Prevention, Atlanta, Georgia. Public domain.)