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White matter abnormalities (T2-weighted MRI) (3)

This T2-weighted MRI identifies marked periventricular changes and subcortical white matter changes in the brain of an elderly male with hypertension as the sole vascular risk factor and with clinical features of mild cognitive impairment and gait disorder. (Contributed by Dr. Cory Toth.)

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Associated Disorders

  • AIDS-related dementia
  • Adrenoleukodystrophy
  • Alzheimer disease
  • Kearns-Sayre syndrome
  • Krabbe disease (globoid cell leukodystrophy)
  • Leigh disease (subacute necrotizing encephalomyelopathy)
  • Susac syndrome
  • cytomegalovirus infection
  • dementia
  • diabetes
  • diabetes mellitus
  • hypertension
  • lacunar stroke
  • metachromatic leukodystrophy
  • migraine
  • mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS)
  • myotonic dystrophy
  • pediatric dysmyelinating disorders
  • pyridoxine deficiency
  • stroke
  • vascular dementia