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Neuropharmacology & Neurotherapeutics
Mar. 06, 2021
Stroke & Vascular Disorders
May. 04, 2021
Revascularization procedures aim to reduce the risk of subsequent stroke by restoring or improving cerebral blood flow, and in some cases aim to reverse the ongoing effects of ischemia. Presently, steno-occlusive lesions in the carotid and vertebrobasilar circulations can be effectively managed by either surgical or endovascular techniques.
Aug. 21, 2018
Jul. 21, 2021
Jul. 26, 2021
Oxcarbazepine is a homologue of the well-known antiepileptic drug carbamazepine. It was developed as an alternative to carbamazepine for patients who had adverse reactions to carbamazepine or diphenylhydantoin. Oxcarbazepine is indicated as a monotherapy for the treatment of partial epilepsy with or without secondary generalization.
Aug. 10, 2020
Excessive yawning is increasingly being recognized as a manifestation of neurologic disorders. According to the thermoregulatory theory of yawning, its function is to cool the brain, and excessive yawning may be a symptom of conditions that increase brain temperature. However, several drugs are reported to induce yawning, and this should be taken into consideration in the differential diagnosis.
Sep. 29, 2020
Fingolimod, an S1P receptor modulator, has an immunosuppressant effect in patients with multiple sclerosis. The neuroprotective effect of fingolimod on relapsing-remitting multiple sclerosis may be due to its modulatory effect on oligodendroglial cells and astrocytes as well as its direct effect on cortical neurons. Adverse events during clinical trials have included bradycardia and atrioventricular block, respiratory and herpesvirus infections, increased liver enzyme levels, hypertension, and macular edema.