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San Diego, CA 92108-2134
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19th-century depiction of ball lightning (“Le globe de feu dans la salle,” or in English, “the globe of fire in the room”). (Courtesy of Wikimedia Commons. Public domain.)
May. 19, 2021
Headache & Pain
Although usually benign, headache can herald serious intracranial disease. Neuroimaging must be considered whenever secondary causes of headache are suspected. The “SNOOP-4” mnemonic provides a list of red flags that would suggest secondary headache and indicate a need for further evaluation, usually with neuroimaging. Neuroimaging should also be strongly considered in unusual primary headaches.
Sep. 01, 2020
Diabetic neuropathies include a variety of disorders that afflict diabetics fairly exclusively and are characterized by variable degrees of peripheral nerve damage. Although chronic distal sensorimotor polyneuropathy is the most common type of diabetic neuropathy, other generalized and focal acute and chronic diabetic neuropathies are not uncommonly encountered in neurologic clinical practice.
Jan. 02, 2021
Congenital cytomegalovirus infection can cause cerebral abnormalities including calcifications, ventriculomegaly, white matter lesions, cortical atrophy, and cortical migration abnormalities. Affected children can have neurologic impairments that range from sensorineural hearing loss to profound mental and motor deficits. It is the most common infection of the developing brain. Although only 5% to 12% of infected infants are symptomatic at birth, more symptoms appear on longer follow-up because it is a chronic persistent infection.
Mar. 06, 2021
Feb. 11, 2021
General Child Neurology
Erb palsy is the most common form of brachial plexus palsy in neonates and is caused by disruption of the upper brachial plexus nerves at cervical nerve roots 5 and 6, and possibly 7 (C5–C7). Clinical findings include shoulder muscle paralysis with an asymmetric Moro reflex, an internally rotated upper arm, an extended elbow due to flexor paralysis, a pronated forearm, and a flexed wrist.
Sep. 16, 2021
Jul. 19, 2021
African sleeping sickness is a devastating epidemic that affects tens of thousands of sub-Saharan Africans. The causative agent usually belongs to 1 of 3 species of the Trypanosoma genus and is transmitted to humans through a vector, the tsetse fly. Neurologic manifestations, including headache, altered EEG, and mood changes, may occur during the initial febrile period before trypanosomes can be detected in the cerebrospinal fluid and are associated with meningeal inflammation.
Oct. 20, 2020