10393 San Diego Mission Rd, Suite 120
San Diego, CA 92108-2134
Toll Free (U.S. + Canada): 800-452-2400
US Number: +1-619-640-4660
(Courtesy of Dr. Daniel Prevedello of the Department of Neurological Surgery at the University of Pittsburgh.)
General Child Neurology
Nov. 01, 2020
Whipple disease is a treatable, multisystem disease caused by infection with Tropheryma whipplei. Whipple disease of the central nervous system may be primary (ie, without evidence of disease outside of the brain) or secondary, occurring in the context of a multisystem condition. Cognitive changes, supranuclear ophthalmoplegia, and altered levels of consciousness are the most common neurologic features.
Dec. 18, 2018
Susac syndrome is typically a triad of encephalopathy, retinopathy, and hearing loss, but may have an atypical presentation. Most patients do not have the clinical triad at the onset of symptoms, but rather recurrences of one or more of the components of the triad. The syndrome is self-limiting and may go on for years, with fluctuations in its course.
Aug. 01, 2021
Blepharospasm is characterized by involuntary eye closure, along with contractions of other facial muscles, oromandibular dystonia, and sometimes cervical dystonia. Excessive contractions of the eyelids, orbicularis oculi adjacent muscles, jaw and neck muscles cause these symptoms. It is a focal dystonia of idiopathic origin.
Jul. 05, 2021
Neuro-Ophthalmology & Neuro-Otology
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is the current nomenclature for small-vessel vasculitides, including microscopic polyangiitis, granulomatosis with polyangiitis, and eosinophilic granulomatosis with polyangiitis. All affect small vessels and involve autoantibody formation against the antigens proteinase 3 and myeloperoxidase. The most commonly affected tissues are the upper and lower respiratory tract, kidneys, skin, and peripheral nerves. Acute exacerbations may be accompanied by nonspecific inflammatory symptoms, such as arthralgia, fever, and myalgia.
Dec. 28, 2016
Nov. 03, 2020
Sep. 18, 2020
Stroke & Vascular Disorders
Up to 15% of all cerebral infarcts occur in young adults (ages 18 to 50 years). Overall, cardiac embolism and nonatherosclerotic vasculopathy are the main etiologies of cerebral infarct in younger patients. Arteriovenous malformation and arterial hypertension are the main etiologies of cerebral hemorrhages. Motor recovery is generally better than that of older patients, although a negative impact on multiple cognitive domains may be observed after a long-term follow up.
Aug. 25, 2020