Neuropathies associated with cryoglobulinemia
Cryoglobulins are serum proteins (predominantly immunoglobulins) that precipitate at temperatures below 37° C and dissolve on rewarming. The majority of cryoglobulins are mixed antigen-antibody complexes that occur in autoimmune or infectious disorders, especially hepatitis C virus infection. Cryoglobulinemic neuropathy is one of the most common forms of vasculitic neuropathy. Sensory neuropathy is the commonest form of neuropathy in mixed cryoglobulinemia.
Jan. 26, 2021