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Bottom-of-sulcus dysplasia in pharmacoresistant focal epilepsy

Bottom-of-sulcus dysplasia in 19-year-old female with pharmacoresistant focal epilepsy. MRI fluid-attenuated inversion recovery (FLAIR) image in a coronal section (A) and an axial section (B). FDG-PET/MRI co-registration is shown in the corresponding coronal (C) and axial (D) sections. Yellow arrows point to the bottom-of-sulcus dysplasia. The lesion was removed surgically, and pathology showed focal cortical dysplasia type IIB. (Contributed by Dr. Hiroki Nariai.)

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Associated Disorders

  • Focal cortical dysplasia
  • Holoprosencephaly
  • Lissencephalies
  • Malformations of the brain
  • Polymicrogyria
  • Schizencephaly
  • Subcortical laminar heterotopia
  • Tuberous sclerosis complex