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Erythema migrans, the characteristic skin lesion of Lyme disease, starts as a red macule or papule, which expands to form a large red ring with central clearing (Contributed by Dr. John Halperin.)
Oct. 20, 2020
Neuropharmacology & Neurotherapeutics
Mycophenolate mofetil is the semisynthetic morpholinoethyl ester of mycophenolate acid, which was developed as an immunosuppressive agent to prevent rejection of transplanted organs. More recently, this agent has been used to treat several inflammatory conditions, including systemic lupus erythematosus, particularly in lupus nephritis. It is currently in clinical trials for autoimmune myasthenia gravis.
Mar. 13, 2021
The sensory symptoms of restless legs syndrome (RLS) are paresthesias and dysesthesias in the calves and legs. Diagnostic criteria for the diagnosis of RLS include (1) an urge to move the legs usually accompanied or caused by uncomfortable and unpleasant sensations in the legs; (2) the urge to move or unpleasant sensations that begin or worsen during periods of rest or inactivity, such as lying or sitting; (3) the urge to move or unpleasant sensations that are partially or totally relieved by movement, such as walking or stretching, at least as long as the activity continues; and (4) the urge to move or unpleasant sensations that are worse in the evening or night than during the day or only occur in the evening or night.
Apr. 25, 2020
May. 28, 2021
Cytomegalovirus (CMV) is a ubiquitous agent responsible for most intrauterine infections. Besides well-known symptoms and findings such as hearing loss
Mar. 06, 2021
Stroke & Vascular Disorders
Fusiform (nonsaccular) aneurysms are elongated dilations of intracranial arteries lacking a distinct neck. Dolichoectasia can be used as an interchangeable term but can also describe a less severe spectrum of arterial dilation and/or tortuosity. Fusiform and dolichoectatic aneurysms can present with ischemic strokes, intracranial hemorrhage, or symptoms related to compression of cranial nerves or brain structures, but they are also often asymptomatic and detected incidentally.
Feb. 21, 2021
Epilepsy & Seizures
Aug. 12, 2021
Apr. 03, 2021