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Cerebral wall in a 26-week fetus with Potter sequence (photomicrograph)

The cortex (C) shows abnormal lamination with many neuron-deficient columns in its upper part. In areas where the plane of section is near transverse, the tangentially cut neuronal columns look like islets of cells surrounded by a cell-deficient neuropil, giving a glomerular appearance (as seen on the right). The underlying white matter (W) shows many arrested heterotopic neurons (arrows), trapped along their migration corridors. (Magnification x20, cresyl violet staining) (Contributed by Dr. Hazim Kadhim.)

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Associated Disorders

  • Anhydramnios
  • Arthrogryposis
  • Bilateral renal agenesis
  • Brachio-oto-renal syndrome
  • Cerebral malformations
  • Chromosomal abnormalities
  • Cystic kidney disease
  • Multiple congenital abnormalities
  • Neuronal migration defects
  • Oligohydramnios
  • Papillorenal syndrome
  • Potter sequence with abnormal gyration of brain
  • Potter sequence with brain malformations
  • Potter sequence with cerebrocortical dysgenesis
  • Potter sequence with defective neuronal migration
  • Potter sequence with gliosis
  • Potter sequence with hydrocephalus
  • Potter sequence with microgyria
  • Potter sequence with neuronal glial ectopias
  • Potter sequence with neuronal heterotopias
  • Prune-belly syndrome
  • Pulmonary hypoplasia
  • Renal agenesis
  • Sirenomelia sequence (caudal regression syndrome)
  • Situs inversus
  • Thomas syndrome
  • Urinary tract malformations
  • VATER syndrome