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Cerebral subcortical white matter in a 26-week fetus with Potter sequence (electron micrograph)

Electron micrograph of a radial glial fiber identified by its glycogen content (arrows), presenting intense lysosomal proliferation. This underlies a process of radial glial fiber transformation into astrocytes. Migrating neuroblasts that need radial glial fibers for their migration would, therefore, be arrested heterotopically within the white matter. Electron microscopic glial staining technique. (Bar=1 micron) (Contributed by Dr. Hazim Kadhim.)

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Associated Disorders

  • Anhydramnios
  • Arthrogryposis
  • Bilateral renal agenesis
  • Brachio-oto-renal syndrome
  • Cerebral malformations
  • Chromosomal abnormalities
  • Cystic kidney disease
  • Multiple congenital abnormalities
  • Neuronal migration defects
  • Oligohydramnios
  • Papillorenal syndrome
  • Potter sequence with abnormal gyration of brain
  • Potter sequence with brain malformations
  • Potter sequence with cerebrocortical dysgenesis
  • Potter sequence with defective neuronal migration
  • Potter sequence with gliosis
  • Potter sequence with hydrocephalus
  • Potter sequence with microgyria
  • Potter sequence with neuronal glial ectopias
  • Potter sequence with neuronal heterotopias
  • Prune-belly syndrome
  • Pulmonary hypoplasia
  • Renal agenesis
  • Sirenomelia sequence (caudal regression syndrome)
  • Situs inversus
  • Thomas syndrome
  • Urinary tract malformations
  • VATER syndrome