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Anaplastic pleomorphic xanthoastrocytoma (histologic appearance)

This section from a 45-year-old woman is more hypercellular, shows more pleomorphism, and has more mitotic figures than a typical low-grade pleomorphic xanthoastrocytoma. The astrocytes demonstrate persistent cytoplasmic lipidization. (hematoxylin and eosin, x 20) (Contributed by Dr. Scott Mintzer.)

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Associated Disorders

  • Cortical dysplasia
  • Epilepsy
  • Ganglioglioma