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A lightweight LINAC mounted on a robotic arm is continuously fed information regarding target movement (eg, respiration) in real-time by 2 orthogonal fluoroscopes. (Figure used with permission from Accuray Inc.)
Neuropharmacology & Neurotherapeutics
Nov. 03, 2020
Nov. 13, 2020
Chorea describes a syndrome characterized by brief, abrupt involuntary movements resulting from a continuous flow of random muscle contractions. When choreic movements are more severe, assuming a flinging, sometimes violent, character, they are called ballism. Vascular disease of the brain is the most common cause of nongenetic chorea in adults.
Aug. 16, 2020
Parkinson disease (PD) is a neurodegenerative disorder that causes bradykinesia, rest tremor, rigidity, and imbalance due to progressive loss of dopaminergic neurons of the substantia nigra pars compacta. Nonmotor symptoms may include dementia, psychosis, orthostatic hypotension, and abnormalities of mood, sleep, and autonomic function.
Feb. 13, 2021
Epilepsy & Seizures
Reflex epileptic seizures are seizures that are elicited by specific extrinsic (light, tactile, acoustic) or intrinsic (thinking, reading, emotional) stimuli. Seizures may be generalized (absences, myoclonic jerks, or generalized tonic-clonic seizures) or focal (visual, sensorimotor, or limbic). EEG is fundamental in the identification of the offending stimuli, with significant clinical and pathophysiological implications.
Mar. 19, 2020
Jun. 07, 2021
Acute necrotizing hemorrhagic leukoencephalitis is a disorder that often follows a virus or mycoplasma infection and evolves rapidly to coma and death. Lesions are hemorrhagic, with fibrinoid necrosis and polymorphonuclear neutrophil infiltration that is associated with demyelination. The devastating immune response may be from excess sensitization to 1 or more unknown antigens. COVID-19 infection induces acute necrotizing hemorrhagic leukoencephalitis.
Mar. 26, 2021
Oct. 21, 2020