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Coronal T1/Gad-weighted MRI showing a nonenhancing masslike in the left uncus containing a central cystic region. (Contributed by Dr. Sarah Lapointe.)
Jan. 04, 2021
Stroke & Vascular Disorders
Cerebral arteriopathies are collectively the most common cause of stroke, accounting for 30% to 40% of strokes in young adults and over 50% in children. Common cerebral vasculopathies in young adults include carotid and vertebral arterial dissection, moyamoya disease, reversible cerebral vasoconstriction syndromes, primary angiitis of the central nervous system, dolichoectasia, sickle cell disease, CADASIL, Fabry disease, and selected genetic and inherited arteriopathies.
Apr. 04, 2020
The basal ganglia are a set of subcortical gray matter structures historically associated with motor function but are also involved in critical cognitive and limbic functions. Emerging evidence suggests that the functional anatomy of the basal ganglia may not be fully accounted for in the standard “rate” model. Various movement disorders can be associated with patterned changes in oscillations and bursts in the substructures of the basal ganglia.
Nov. 21, 2020
Hemiplegia is a total paralysis of the arm, leg, and sometimes the face on one side of the body, whereas hemiparesis is partial paralysis on one side of the body. Hemiplegia and hemiparesis are not diseases but a response of the central nervous system to a variety of insults. Clinical manifestations, course, and outcome of acute hemiplegia vary depending on the etiology.
Nov. 08, 2020
Neuropharmacology & Neurotherapeutics
Sep. 02, 2020
Presbyosmia, the age-related loss of smell, is common in the elderly and results from normal aging, certain diseases (especially Parkinson disease and dementia with Lewy bodies), medications, surgical interventions, and prior environmental exposures. Clinically significant olfactory loss is frequently unrecognized. Impaired olfaction adversely affects quality of life, psychological and physical health, and the enjoyment of eating and may pose a safety risk.
Oct. 21, 2020
Sep. 06, 2020
Stiff-person syndrome is a rare disorder that causes continuous muscle contractions with spasms, abnormal postures, and progressive disability. It is often associated with other autoimmune signs and symptoms as well as nonspecific and organ-specific autoantibodies. The symptoms of stiff-person syndrome likely relate to cortical and spinal cord hyperexcitability secondary to reduction of GABA.
Aug. 16, 2020