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This study demonstrates the feeding artery (arrow) of this malformation, as well as a large venous aneurysm superiorly. (Contributed by Dr. Sherman Stein.)
Neuropharmacology & Neurotherapeutics
Sep. 29, 2020
Headache & Pain
Hemiplegic migraine is characterized by migraine with aura including motor weakness. Recurrent coma, encephalitis, or cerebellar ataxia in a patient with a family history of migraine and cerebellar ataxia could be the presenting symptoms of familial hemiplegic migraine. Attacks may be provoked by emotional stress, mild head trauma, angiography, or exertion. Most hemiplegic patients recover completely between attacks, but permanent sequelae have been reported.
Dec. 06, 2020
Anti-GD1b IgG or IgM antibodies are associated with acute or chronic ataxic neuropathy syndromes respectively, which may arise as acute postinfectious syndromes or as chronic paraproteinemia-associated syndromes. Sensory ataxic variants of Guillain Barré syndrome are often associated with anti-GD1b IgG antibodies.
Feb. 18, 2019
Serotonin syndrome is due to the toxic effect of excess of serotonin activity. It may result from an overdose of serotonergic drugs as well as drug interactions, the most common of which occurs between serotonergic agents and MAO inhibitors. Clinical manifestations inlude mental status change, agitation, myoclonus, hyperreflexia, diaphoresis, shivering, tremor, diarrhea, incoordination, and fever.
Sep. 13, 2020
General Child Neurology
Chiari malformation describes a group of structural defects of the cerebellum, characterized by brain tissue protruding into the spinal canal. For most patients, Chiari malformation is a congenital malformation, arising from an embryologic defect in the formation of neural and craniovertebral structures. Chiari malformations are often associated with myelomeningocele, hydrocephalus, syringomyelia, and tethered cord syndrome. Some categorize type 1 malformations as “adult type” and type 2 malformations as “congenital type.”
Jun. 12, 2020
Jul. 08, 2021
Asymptomatic hyperCKemia indicates a finding of persistent and abnormally high serum levels of creatine kinase (CK) in an asymptomatic person, whether or not the etiology has been found. An increased serum CK level is taken to mean that the integrity of the skeletal muscle membrane has been affected; an increased serum CK level is also a hallmark of muscle disease, either hereditary or acquired. Statin use is probably the most common cause of asymptomatic hyperCKemia.
May. 31, 2021
Epilepsy & Seizures
Myoclonic status epilepticus is used to describe a variety of clinical states that involve a prolonged period of frequent spontaneous myoclonic jerks. It can be associated with generalized epilepsy syndromes, neurodegenerative disease, infectious or inflammatory neurologic disease, toxic-metabolic states, and following anoxic brain injury.
Sep. 20, 2020