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Foamy oligodendroglia cell (high-magnification electron microscopy)

Cytoplasmic membranous structures and abnormal mitochondria. A narrow rim of the nucleus is visible at the right lower border. Because the volume of the foamy oligodendroglial cells is much greater than the size of the nucleus, there were numerous cell cytoplasmic collections in the white matter. These sections containing the nucleus most likely represent an eccentric, tangential, small section of the entire foamy oligodendroglial cell. (Contributed by Dr. Raphael Schiffmann.)

Associated Disorders

  • Leukodystrophy with vanishing white matter