Autoantibodies: disease markers
Autoreactive antibodies against central or peripheral nervous system antigens may be useful for the diagnosis of several neurologic diseases. In paraneoplastic neurologic disorders, their detection can also help identify an associated cancer at a stage before it is clinically overt, potentially leading to early successful therapy. The sensitivity and specificity and the reliability of the commercially used techniques is important to evaluate in order to avoid useless tests.
Jan. 30, 2017