10393 San Diego Mission Rd, Suite 120
San Diego, CA 92108-2134
Toll Free (U.S. + Canada): 800-452-2400
US Number: +1-619-640-4660
Attending Pediatric Neurologist and Epileptologist
Division of Pediatric Neurology
University of British Columbia
Dr. Datta of the University of British Columbia has no relevant financial relationships to disclose.
May. 26, 2021
Apr. 01, 2021
Hereditary spastic paraplegias (HSPs) are a hereditary group of disorders with intrafamilial and interfamilial variations in clinical presentations. Most cases present with a slowly progressive gait disturbance of insidious onset. Spasticity of the lower limbs, which can be slightly asymmetrical, occurs in the absence of limb weakness and is often only demonstrable on walking. Additional neurologic features such as cognitive impairment, ataxia, dysarthria, neuropathy, or seizures are seen in more than half of cases and can be the presenting feature.
Nov. 20, 2020