Epilepsy & Seizures
Gelastic seizures are characterized by recurrent bouts of unprovoked and stereotyped laughter. They are classically associated with hypothalamic hamartoma but may also be secondary to focal pathology in the frontal or temporal lobes and, rarely, the parietal lobe. When they are associated with hypothalamic hamartomas, gelastic seizures are typically intractable to medical therapy and may be one of the first manifestations of a syndrome characterized by multiple seizure types, precocious puberty, and an epileptic encephalopathy.
Dec. 29, 2020