General Child Neurology
Perinatal hypoxic-ischemic encephalopathy
Jan. 30, 2024
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Toll Free (U.S. + Canada): 800-452-2400
US Number: +1-619-640-4660
Support: service@medlink.com
Editor: editor@medlink.com
ISSN: 2831-9125
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(Fukutin related protein muscular dystrophy, FKRP) Alpha-dystroglycan immunohistochemical stain (A) reveals markedly decreased or absent immunoreactivity in most muscle fibers. FKRP encodes a putative glycosyltransferase protein that is involved in alpha-dystroglycan glycosylation; alpha-dystroglycan levels are reduced in this condition. Reactivity for beta dystroglycan in the same patient is preserved (B). (Contributed by Dr. Andrew Waclawik.)