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Immunohistochemical staining of bladder paraganglioma (SDHB)

Immunohistochemical staining of the bladder paraganglioma with SDHB, one of four protein subunits forming succinate dehydrogenase. Immunohistochemical evaluation of SDHB is a tool pathologists use to screen paragangliomas for possible mutations in SDHx genes. (Source: Wang Z, Liu F, Li C, et al. Case report: octreotide plus CVD chemotherapy for the treatment of multiple metastatic paragangliomas after double resection for functional bladder paraganglioma and urothelial papilloma. Front Oncol 2023;12:1072361. Creative Commons Attribution 4.0 International [CC BY 4.0] license,