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Best disease (EOG)

(A) The electro-oculogram in Best disease is flat, eg, there is no difference in the standing potential across the eye in the light and dark. Hence, the light/dark ratio in this patient is 1. (B) This figure is of a normal electro-oculogram for comparison purposes. (Contributed by Dr. James Walters.)

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Associated Disorders

  • Bassen-Kornzweig disease
  • Cushing syndrome
  • Kearns-Sayre syndrome
  • Lawrence-Moon-Biedl syndrome
  • Mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS)
  • Ocular paraneoplastic syndromes
  • Refsum disease
  • Usher syndrome
  • gastroesophageal reflux disease
  • posterior vitreous detachment
  • retinal detachment
  • systemic arterial hypertension
  • systemic lupus erythematosus