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Early macular hole with vitreomacular traction

(A) Vitreomacular traction is one mechanism by which macular holes can form. This hole is small and not well visualized in this picture. (B) In this OCT cross section, a faint representation of the vitreal interface can still be seen tugging on the macula (upper left). (Contributed by Dr. James Walters.)

Associated Disorders

  • Bassen-Kornzweig disease
  • Cushing syndrome
  • Kearns-Sayre syndrome
  • Lawrence-Moon-Biedl syndrome
  • Mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS)
  • Ocular paraneoplastic syndromes
  • Refsum disease
  • Usher syndrome
  • gastroesophageal reflux disease
  • posterior vitreous detachment
  • retinal detachment
  • systemic arterial hypertension
  • systemic lupus erythematosus