Neuropharmacology & Neurotherapeutics
Drug-induced aseptic meningitis
May. 19, 2023
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Many enzymes catalyze side reactions leading to the production of abnormal metabolites. These metabolites may be toxic (eg, if they inhibit other enzymes). Fortunately, under normal circumstances, these abnormal metabolites are generally destroyed by metabolite repair enzymes and so become unable to exert toxic effects. (Source: Veiga-da-Cunha M, Van Schaftingen E, Bommer GT. Inborn errors of metabolite repair. J Inherit Metab Dis 2020;43:14-24. Creative Commons Attribution License.)