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Grade 3 lissencephaly (MRI)

MRI of a child with isolated lissencephaly sequence shows less severe (grade 3) lissencephaly with frontal pachygyria and posterior agyria, illustrating the variability of the gyral malformation. (Contributed by Dr. William Dobyns.)

Related Media

Associated Disorders

  • Classic lissencephaly
  • Cobblestone (type II) lissencephaly
  • Double cortex syndrome
  • Fukuyama-type congenital muscular dystrophy
  • Lennox-Gastaut syndrome
  • Lissencephaly with cerebella hypoplasia
  • Miller-Dieker syndrome
  • Muscle-eye-brain disease
  • Norman-Roberts syndrome
  • Partial lissencephaly
  • Polymicrogyria (pachygyria-polymicrogyria)
  • Schinzel-Giedion syndrome
  • Schizencephaly
  • Subcortical band heterotopias
  • Walker-Warburg syndrome
  • West syndrome
  • Winter-Tsukuhara syndrome
  • X-linked lissencephaly
  • X-linked lissencephaly with abnormal genitalia (XLAG)