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Pineal germinoma imaging

T1-weighted, gadolinium-enhanced coronal and axial MRI scans of a 16-year-old boy with a biopsy-proven pineal region germinoma before (A, B) and after (C, D) one course of chemotherapy with cis-platinum and etoposide. The lobulated appearance; dense, homogeneous enhancement; sharply defined margins; and lack of surrounding edema are characteristic. Artifact due to ventriculo-peritoneal shunt placement is seen on the post-operative, post-chemotherapy scans (C, D). (Contributed by Dr. Santosh Kesari.)

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Associated Disorders

  • Choriocarcinoma
  • Diabetes insipidus
  • Embryonal carcinoma
  • Endodermal sinus tumor
  • Hydrocephalus
  • Immature teratoma
  • Mature teratoma
  • Pan-hypopituitarism
  • Precocious puberty
  • Radiation-induced nervous system injury