Sign Up for a Free Account
  • Updated 09.08.2009
  • Released 02.28.2005
  • Expires For CME 09.08.2012

Haemophilus influenzae meningitis

Introduction

This article includes discussion of Haemophilus influenzae meningitis, Haemophilus influenzae, Haemophilus influenzae type b, Hib, H influenzae, and H flu. The foregoing terms may include synonyms, similar disorders, variations in usage, and abbreviations.

Overview

Meningitis is the most serious form of Haemophilus influenzae infection, historically causing significant mortality and morbidity, especially among children. Vaccination against H influenzae type b has dramatically decreased the impact of this disease, making recognition more difficult when it occurs. In this article, the author reviews the clinical manifestations and pathophysiology of H influenzae infection, with emphasis on the key features useful for making a timely diagnosis. Recent research has elucidated the factors involved in the inflammatory response to this organism, and new PCR-based techniques for confirming the diagnosis have been developed. The most recent vaccination guidelines and current treatment recommendations are discussed.

Historical note and terminology

Haemophilus influenzae was first isolated by Pfeiffer during the 1889 influenza pandemic (69), and it was believed to be the causative agent of influenza. It was called the “influenza bacillus.” Eventually, the error of this diagnostic association was recognized. The organism was given the genus name Haemophilus, meaning “blood-loving,” and the species name influenzae in recognition of the historical association.

Start a MedLink Neurology trial
to unlock 3 free articles.

  • Nearly 3,000 illustrations, 
including video clips of 
neurologic disorders.

  • Every article is reviewed by our esteemed Editorial Board for accuracy and currency.

  • Full spectrum of 
neurology in 1,200 
comprehensive articles.

Questions or Comment?

MedLink, LLC

10393 San Diego Mission Rd, Suite 120

San Diego, CA 92108-2134

Toll Free (U.S. + Canada): 800-452-2400

US Number: +1-619-640-4660

Support: service@medlink.com

Editor: editor@medlink.com