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  • Updated 08.28.2023
  • Released 06.26.1995
  • Expires For CME 08.28.2026

Headache associated with intracranial neoplasms



Headaches associated with intracranial neoplasms are common. This article discusses the epidemiology, pathogenesis, and clinical presentation of brain tumor-associated headaches. In addition, uncommon headache syndromes caused by brain tumors, headaches precipitated by the initial treatment of brain tumors, as well as headaches occurring as late complications of brain tumor treatment are described. The approach to new headaches in patients with known malignancies and the treatment of brain tumor headaches are briefly discussed.

Historical note and terminology

Headache has been recognized as a common symptom of brain tumors for many years. In the 1940s, a series of classic papers described the clinical characteristics and mechanisms of brain tumor-associated headache (61; 49). With improved neuroimaging and the resultant earlier diagnosis, the spectrum of tumor-associated headache has expanded beyond these classical descriptions.

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ISSN: 2831-9125