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  • Updated 12.28.2023
  • Released 06.06.2012
  • Expires For CME 12.28.2026

Primary prevention of stroke



Prevention of stroke and transient ischemic attack includes both conventional approaches to vascular risk factor management (blood pressure lowering, cholesterol reduction with statins, smoking cessation, and antiplatelet therapy) and more specific interventions, such as carotid revascularization or anticoagulation for atrial fibrillation. In this article, the authors discuss effective interventions for optimal primary stroke prevention.

Key points

• Key risk factors for stroke include the following:

- alcohol
- asymptomatic carotid artery disease
- atrial fibrillation
- cigarette smoking
- diabetes mellitus
- dietary factors and obesity
- estrogens
- hyperhomocysteinemia
- hypertension
- lipid abnormalities
- migraine
- physical activity (lack of)
- sickle cell disease

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