Neuro-Ophthalmology & Neuro-Otology
Vogt-Koyanagi-Harada syndrome is primarily an ocular inflammatory disease, but the prodrome often includes signs and symptoms that bring the patient to a neurologist, including headache, meningeal signs, and CSF pleocytosis. Melanin pigment-containing cells are often involved, including the retinal pigment epithelium in the eye producing “sunset glow” fundus appearance and cutaneous melanocytes producing vitiligo and poliosis. The disease is encountered more frequently in persons of Asian, Latin, and Mediterranean descent than in other ethnic groups.
Jul. 25, 2020