Neuropharmacology & Neurotherapeutics
Sep. 12, 2021
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Neurosyphilis is an infection that affects the coverings of the brain, the brain itself, or the spinal cord. It can occur in people with syphilis, especially if their condition is left untreated. Neurosyphilis is different from syphilis. Syphilis is a sexually transmitted disease (STD) with different signs and symptoms. There are five types of neurosyphilis:
General paresis and tabes dorsalis are now less common than the other forms of neurosyphilis because of advances made in prevention, screening, and treatment. People with HIV/AIDS are at higher risk of having neurosyphilis.
Penicillin, an antibiotic, is used to treat syphilis. Some medical professionals recommend another antibiotic called ceftriaxone for neurosyphilis treatment. Treatment outcomes are different for every person.
Prognosis can change based on the type of neurosyphilis and how early the disease is diagnosed and treated. Individuals with asymptomatic neurosyphilis or meningeal neurosyphilis usually return to normal health. People with meningovascular syphilis, general paresis, or tabes dorsalis usually do not return to normal health, although they may get much better. Individuals who receive treatment many years after they have been infected have a worse prognosis.
How can I or my loved one help improve care for people with neurosyphilis?
Consider participating in a clinical trial so clinicians and scientists can learn more about neurosyphilis and related disorders. Clinical research uses human volunteers to help researchers learn more about a disorder and perhaps find better ways to safely detect, treat, or prevent disease.
All types of volunteers are needed—those who are healthy or may have an illness or disease—of all different ages, sexes, races, and ethnicities to ensure that study results apply to as many people as possible, and that treatments will be safe and effective for everyone who will use them.
Where can I find more information about neurosyphilis?
Information may be available from the following resources:
Content source: https://www.ninds.nih.gov/health-information/disorders/neurosyphilis Accessed June 23, 2023.
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