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Chorea, tics, stereotypies, and ataxia in neuroacanthocytosis

Chorea, tics, stereotypies, and ataxia in neuroacanthocytosis

This young man has a 2-year history of incoordination, unsteady gait, finger-snapping stereotypy, and orofacial tics with sucking, clicking, and smacking sounds as well as tongue- and cheek-biting. He displays a slow chorea associated with typical bending movements of the trunk, giving him the appearance of a “rubber man.” These features are characteristic of neuroacanthocytosis. (Contributed by Dr. Joseph Jankovic.)

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Associated Disorders

  • Benign hereditary chorea
  • Chorea
  • Epilepsy
  • HARP syndrome (hyperprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration)
  • Hallervorden Spatz syndrome
  • Huntington-disease-like neurodegenerative disorder
  • Juvenile Huntington disease
  • Neuroacanthocytosis
  • Neurodegeneration with brain iron accumulation (formerly known as Hallervorden Spatz syndrome)
  • Obsessive-compulsive disorder
  • Paroxysmal choreas
  • Paroxysmal exercise-induced dyskinesia
  • Paroxysmal hypnogenic dyskinesia
  • Paroxysmal kinesigenic dyskinesia
  • Paroxysmal nonkinesigenic dyskinesia
  • Postcardiopulmonary bypass chorea
  • Rheumatic chorea
  • Rheumatic fever
  • Streptococcal infection
  • Tourette syndrome
  • Wilson disease
  • Wilson disease