Epilepsy & Seizures
Epilepsy and psychoses
Nov. 29, 2021
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Toll Free (U.S. + Canada): 800-452-2400
US Number: +1-619-640-4660
Support: service@medlink.com
Editor: editor@medlink.com
ISSN: 2831-9125
Nearly 3,000 illustrations, including video clips of neurologic disorders.
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This boy's first sign of developmental delay began after the first year. He had an enlarged head by 18 months and died at age 6 years. (A) In the cerebral cortex, Rosenthal fiber accumulations are evident in the characteristic subpial and perivascular sites, whereas elsewhere in the cortex only scattered Rosenthal fibers are seen. (B) The cerebral white matter contains diffuse and extensive deposits of Rosenthal fibers, as well as perivascular accumulations. Almost no myelin is present, which would normally stain darkly with this Luxol Fast blue. (x82 for A and B) (Reprinted with permission. Johnson AB. Alexander disease. In: Moser HW, editor. Neurodystrophies and neurolipidoses. Handbook of clinical neurology. Vol. 66, revised series vol. 22. Amsterdam: Elsevier, 1996:701-10.)