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Immune-mediated cerebellar ataxia clinical course

(A) Six clinical courses of immune-mediated cerebellar ataxias: (a) full recovery, (b) partial recovery, (c) stabilization, (d) relapse, (e) gradually progressive, and (f) rapidly progressive. PIC: postinfectious cerebellitis; OMS: opsoclonus myoclonus syndrome; Anti-GAD: anti-GAD ataxia; PCDs: paraneoplastic cerebellar degenerations. (B) Schematic diagram of the concept of cerebellar reserve. (Contributed by Dr. Hiroshi Mitoma.)

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Associated Disorders

  • Autoimmune disorders (thyroid diseases, type 1 diabetes mellitus, pernicious anemia)
  • Celiac disease in gluten ataxia