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Segmental demyelination with evidence of inflammation in chronic inflammatory demyelinating polyradiculoneuropathy (photomicrograph)

Teased fibers of sural nerve showing paranodal and segmental demyelination in chronic inflammatory demyelinating polyradiculoneuropathy (x30 before magnification). (Courtesy of Dr. R. Wollmann, University of Chicago.)

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Associated Disorders

  • Alopecia universalis
  • Carcinoma
  • Castleman disease
  • Cat scratch disease
  • Chronic active hepatitis
  • Diabetes
  • Eczema
  • Hemodialysis
  • Hodgkin disease
  • Human immunodeficiency virus-1 infection
  • Inflammatory bowel disease
  • Iritis
  • Isaacs syndrome (neuromyotonia)
  • Malignant melanoma
  • Membranous glomerulonephritis
  • Mixed connective tissue disease
  • Monoclonal gammopathy of undetermined significance
  • Osteosclerotic myeloma
  • Peritoneal dialysis
  • Psoriasis
  • Seminoma
  • Systemic lupus erythematosus
  • Thyrotoxicosis