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Schematic representation of DNA methylation

DNA methyltransferase (DNMT) catalyzes the conversion of cytosine to 5’methyl-cytosine, typically acting on cytosines that are followed by a guanine (ie, CpG motifs-cytosine and guanine separated by only one phosphate). Source: (Zakhari 2013). Public domain. Note: The legend for this figure has been modified.

Associated Disorders

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  • Hyperkalemia
  • Nutritional deficiency