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Aug. 16, 2020
Stroke & Vascular Disorders
Hemorrhagic transformation is a complication of ischemic stroke, occurring in about 10% of patients. It encompasses a broad spectrum of secondary bleeding, ranging from minor petechial bleeding (hemorrhagic infarct) to major mass-producing hemorrhage (parenchymal hematoma). Only parenchymal hematoma, seen in about 3% of patients, is associated with adverse outcome.
Apr. 26, 2020
May. 21, 2021
Epilepsy & Seizures
Atypical absences are epileptic seizures that primarily occur in children with severe learning and neurologic disabilities of epileptic encephalopathies,
Oct. 14, 2019
Mar. 10, 2021
Classic chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) consists of a symmetrical proximal and distal weakness with variable sensory symptoms that exhibits either a relapsing, stepwise progressive or steadily progressive course. Aside from limb weakness, patients often have fatigue, numbness, tingling, or tight sensation in their extremities. Painful symptoms include burning, aching, tenderness, or jabbing feelings.
Oct. 10, 2020
Childhood Degenerative & Metabolic Disorders
Arginase 1 deficiency is an inherited urea cycle disorder that may cause hyperammonemia. Arginase 1 deficiency mainly affects the central nervous system
Oct. 03, 2019
Insomnia appears in several forms: (1) difficulty initiating sleep, (2) repeated or lengthy awakenings, (3) early awakenings, (4) inadequate total sleep time, or (5) poor quality of sleep as reflected by its consequences, including daytime sleepiness. The ICSD-3 defines 3 different classification systems for insomnia: chronic insomnia disorder, short-term insomnia disorder, and other insomnia disorder. Complications of insomnia include impaired responses to infections, increase in inflammation, higher levels of the stress hormone cortisol, and other biomarkers related to fatigue and poor health.
Oct. 11, 2020