Progressive supranuclear palsy
Progressive supranuclear palsy (PSP) is a late-onset degenerative disease of the CNS characterized by balance difficulties, vertical gaze palsy, dysarthria, dysphagia, and axial dystonia. Ophthalmoparesis, especially downgaze impairment, is a classic clinical feature of PSP that may appear later in the course of the disorder. Multiple subtypes of PSP have been identified, including the classic Richardson syndrome, progressive supranuclear palsy-parkinsonism (PSP-P), or pure-akinesia-with-gait-freezing (PAGF).
Apr. 07, 2021