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Pituitary apoplexy precipitated by systemic chemotherapy (sagittal post-contrast T1-weighted MRI)

MRI from a 31-year-old man with pituitary apoplexy precipitated by systemic chemotherapy demonstrates expansion of the sella consistent with a prior slow-growing tumor. Enhancement of the sphenoid sinus mucosa is also seen (gray arrows), which has been linked to higher intrasellar pressures and more severe pituitary apoplexy. (Source: Hamrick FA, Findlay MC, Rennert RC, Budohoski KP, Couldwell WT. Pituitary apoplexy precipitated by systemic chemotherapy. Cureus 2022;14[3]:e23004. Creative Commons Attribution License [CC-BY 4.0].)

Associated Disorders

  • Acromegaly
  • Bleeding diatheses
  • Chromophobes
  • Cushing disease
  • Diabetes insipidus
  • Diabetes mellitus
  • Drug reactions
  • Gonadotropinomas
  • Head trauma
  • Hemolytic crises
  • Hypertension
  • Ischemic necrosis
  • Macroprolactinomas
  • Meningitis
  • Microprolactinomas
  • Pituitary macroadenoma
  • Pituitary microadenoma
  • Sheehan syndrome
  • Sickle cell disease
  • Temporal arteritis
  • Tuberculosis