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Virchow triad

Rudolf Virchow proposed in 1862 that the pathophysiology of thrombosis involved a triad of interrelated factors: damage to the blood vessel wall, stasis of blood flow, and alterations in blood coagulability. (Contributed by Dr. Steven Lentz.)

Associated Disorders

  • Activated protein C resistance
  • Antiphospholipid antibody syndrome
  • Antithrombin III deficiency
  • Deep venous thrombosis
  • Myeloproliferative neoplasms
  • Myocardial infarction
  • Protein C deficiency
  • Protein S deficiency
  • Pulmonary embolism
  • SARS-Co-V-2