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Progressive meningeal disease in acute lymphoblastic leukemia (MRI) (1)

These MRIs were performed on a patient receiving chemotherapy for acute lymphoblastic leukemia. The T1-weighted images showed evidence of an area of hyperintense signal without contrast enhancement in the bilateral occipital lobes and possibly in the right thalamus. Hyperintense signal was evident in these areas on FLAIR images. Diffusion-weighted images revealed no obvious abnormality with the exception of a subtle, hyperintense signal along the cortex of the right occipital and temporal lobes and left occipital lobe. (Contributed by Dr. Jon Glass.)

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